Leaky Gut Syndrome (Antraja Vrana)
त्वक्सिरामांसमेदोऽस्थिस्नायुमर्मान्तराश्रयाः ।
व्रणस्थानानि निर्दिष्टान्यष्टावेतानि संग्रहे ।। २६ ।।
Leaky Gut Syndrome: Symptoms, Causes, Types, Do's, Don'ts, Yoga, Ayurvedic Reference and Treatment : Complete Ayurveda Details
Leaky gut syndrome, also known as intestinal hyperpermeability is a serious condition caused by the loss of tight junction of the intestinal walls. In addition to break down and absorption of food substances, the digestive system also plays an important role in protecting our body from harmful substances. The walls of the intestine act as a barrier, thereby preventing bacterias and other harmful substances entering the bloodstream. When the tight junction of intestinal walls becomes more permeable, it will allow these harmful substances to enter the bloodstream. This phenomenon is known as leaky gut. In this condition, widespread inflammation and permanent damage of intestinal viscera may occur if left untreated.
We can correlate the condition “Antraja Vrana” as leaky gut syndrome. Vrana means tearing or splitting of any part of the body. Vrana also means discontinuity of the skin or any other tissues. Here in leaky gut syndrome, the continuity of the intestinal wall is lost, therefore it can be taken as Antraja Vrana. The word “Antra” in Sanskrit language denotes ‘Intestine’.
Acharya Susruta have mentioned about various features of Antraja Vrana. The symptoms include Atisara (diarrhea ), malabandha (constipation ), kuksha sula (stomach pain ), atopa (bloating of abdomen ) etc. Early detection of the condition is important for the fast recovery.
Leaky gut syndrome is a rapidly progressing condition. Controlling our diet and intake of medicines mentioned in Ayurveda can prevent the complications of this condition.
Signs and Symptoms of Leaky gut syndrome - Antraja Vrana
Leaky gut syndrome may result in digestive as well as other system failures. Various symptoms observed in this condition are –
Digestive Symptoms :-
- Abdominal bloating
- Diarrhea
- Stomach pain
- Abdominal cramps
- Food sensitivity and
- Delayed digestion
Other observed symptoms include –
- Sinusitis
- Eczema
- Chronic skin infection
- Migraine
- Hyperthyroidism
- Joint pains
- Chronic fatigue
- Weight gain
- Depression and
- Mood swings
Ayurvedic reference of Leaky gut syndrome - Antraja Vrana

Causes of Leaky gut syndrome - Antraja Vrana
Leaky gut syndrome occurs due to the discontinuity of intestinal walls, allowing toxins and bacterias to enter the bloodstream there by causing inflammation. Various factors are responsible for the loss of continuity of intestinal walls including –
- Chronic inflammation
- Nutritional deficiency
- Fatty acid deficiency
- Chronic stress
- Improper digestion
- High alcohol intake
- Parasites
- Pathogenic bacterias
- Yeast infections and
- Other chronic systemic disorders.
Triggering Factors of Leaky gut syndrome - Antraja Vrana
Various conditions may result in increasing the chances of occurrence of leaky gut syndrome. They are as follows –
- Gastritis
- HIV – AIDS
- Alcoholism
- Type 1 diabetes
- Irritable bowel syndrome
- Inflammatory bowel disease and
- Irregular diet
Diagnosis of Leaky gut syndrome - Antraja Vrana
Diagnosis of leaky gut syndrome is difficult as it mimics various other chronic conditions. We can detect the condition via endoscopy, CT Scan etc. High levels of IgA antibodies may also indicate leaky gut syndrome.

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Diet for Leaky gut syndrome - Antraja Vrana
Do's (Pathya’s)
- Pomegranate
- Moderate exercises without severe sweating
- Timely food intake
- Easy to digest food materials
- Gooseberry and
- Barley
Don'ts (Apathya’s)
- Coffee
- Chilly and Garlic for the treatment period
- Heavy to digest food substances like deep fries and synthetic food materials
- Alcohol and
- Untimely food intake.
Yoga and Pranayama for Leaky gut syndrome - Antraja Vrana
As explained earlier, a healthy lifestyle and diet pattern is essential in controlling leaky gut syndrome. Pranayama and yoga helps in proper oxygen intake and reduces the amount of toxic substances produced inside the body. Yoga techniques like
- Gomukhasana,
- Tadasana,
- Chakrasana,
- Vajrasana etc. helps in the proper working of the digestive system and also cures various abdominal disorders.

Management of Leaky gut syndrome - Antraja Vrana
The major step for management of this fatal condition is by taking necessary precautionary methods and controlling diet habits. Food items like junk foods, spicy foods and meat should be avoided from the diet for the treatment period.
Ayurvedic treatment of Leaky gut syndrome - Antraja Vrana
Management of leaky gut syndrome – antraja vrana should be started by correcting the diet pattern. Healthy food intake regimen and lifestyle are more important than internal medicines in the management of this condition.
Internal Medicines of Leaky gut syndrome - Antraja Vrana
- Amruthotharam kashayam
- Guduchyadi kashayam
- Drakshadi kashayam
- Kalyanaka ghritam
- Dadimadi ghritam
- Tiktaka ghritam and
- Sukumara rasayanam
Single herbs used to treat Leaky gut syndrome - Antraja Vrana
- Amalaki (Emblica officinalis )
- Draksha (Vitis vinifera) and
- Yava (Hordeum vulgare)
References:
- Shloka No. 6; Chapter No. 1 – Dvivraniyam Chikitsitam, from Susruta Samhita Chikitsa Sthanam written by Acharya Susrutha.
- Shloka No. 26, Chapter No. 25 – Dvivraniya Chikitsitam, from Charaka Samhita Chikitsa Sthanam by Acharya Agnivesa.
- K.R. Srikantha Murthy. Ashtanga Samgraha of Vagbhata, English translator Vol. 1, Chaukhambha Orientalia, Sutrasthana 4/14-16, p. 61.
- Sharma H. Leaky Gut Syndrome, dysbiosis, ama, free radicals and natural antioxidants. AYU. 2009; 30: 88-105.
Article Written By: Dr. Sahil Gupta (B.A.M.S., M.H.A.)